Characteristics of NDM-1-producing Escherichia coli isolates that belong to the successful and virulent clone ST131.

نویسندگان

  • Gisele Peirano
  • Paul C Schreckenberger
  • Johann D D Pitout
چکیده

An NDM-1 carbapenemase-producing Escherichia coli isolate of sequence type 131 (ST131) that belonged to phylogenetic group B2 was obtained from a patient with a urinary tract infection who returned to the United States after a recent hospitalization while visiting India. NDM-1-producing E. coli ST131 had significantly more virulence factors than NDM-1-producing E. coli ST101, previously isolated from a patient in Canada. The presence of NDM β-lactamases in a very successful and virulent E. coli sequence type is of concern.

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References 1. Yokota S, Sato T, Okubo T, Ohkoshi Y, Okabayashi T, Kuwahara O, et al. Prevalence of fluoroquinolone-resistant Escherichia coli O25:H4-ST131 (CTX-M-15-nonproducing) strains isolated in Japan. Chemotherapy. 2012;58:52–9. http://dx.doi.org/10.1159/000336129 2. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing (M100-S25). Wayn...

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 55 6  شماره 

صفحات  -

تاریخ انتشار 2011